H.H. Chen-Mayer, and R. Tosh
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA
Water calorimetry is employed to establish a primary reference standard for radiation dosimetry by measuring the temperature rises in a water phantom (a cube of about 30 cm x 30 cm x 30 cm) subjected to a beam of ionizing radiation. We use COMSOL Multiphysics to model the system using the Heat Transfer module and the Incompressible Navier-Stokes module with a geometry of 2D-axial ...
Magnetic Fields and Materials for Medical Bone Reconstruction Assisted by Advanced Finite-Element Simulations
A. Sytcheva and T. Herrmannsdörfer
Hochfeld-Magnetlabor Dresden, Forschungszentrum Dresden-Rossendorf, Dresden, Germany
We address the use of magnetic fields, forces, and materials for medical purposes. In particular, the treatment of osteochondral lesions is aimed for. To support ongoing activities in this field of research, last advances in using Finite Element Analysis (FEA) for the simulation of relevant processes, like magnetic targeting and magnetic fixation are reported. The availability of advanced ...
Modelling Nutrient Transport in a Hollow-Fiber Membrane Bioreactor with Considerating the sub-Cellular Scale Mass Transfer
N. S. Abdullah1, D. B. Das2, and D. R. Jones1
1Department of Engineering Science, University of Oxford, Oxford, UK
2Department of Chemical Engineering, Loughborough University, Leicestershire, UK
Current bone tissue engineering protocols allow ex vivo growth of soft bone tissues in bioreactors. Recent experimental studies suggest that hollow fiber membrane bioreactors (HFMBs) may be used for growing 3-dimensional, clinically viable bone tissues. In order to facilitate the design of the HFMB for growing bone tissues, it is necessary to elucidate the quantitative relationships between cell ...
C. Morgan, N. Kenkare, M. Williams, A. Peterson, and D. Williams
Alcon Eye Care Division of Novartis R&D, Duluth, GA
Alcon Eye Care Division of Novartis R&D and Georgia Institute of Technology Co-op Program, GA
Introduction of silicone hydrogel contact lens materials provided products of unprecedented capability to deliver oxygen to the eye during wear. One additional material characteristic of interest is the material’s permeability to ions. This paper discusses descriptive tools and optimization of an impedance method of characterizing ion permeability. A physical model of conductive paper with ...
Image-Based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-Pulmonary Applications
F.K. Hermans, R.M. Heethaar, R.T. Cotton, and A. Harkara
VU University Medical Center, Amsterdam, The Netherlands
Simpleware Ltd., Exeter, United Kingdom
For medical diagnostic purposes there is an increasing need for non- (or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the heart and Electric Impedance Tomography (EIT) is used for investigating lung tissue condition. This paper ...
Passive and Active Deformation Processes of 3D Fibre-Reinforced Caricatures of Cardiovascular Tissues
A. Di Carlo, P. Nardinocchi, T. Svaton, and L. Teresi
Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
Dept. of Structural & Geotechnical Engineering, Università di Roma La Sapienza, Roma, Italy
Dept. of Mathematics, University of West Bohemia, Pilsen, Czech Republic
In this paper, we present a mathematical model of contractile elastic solids meant to simulate various districts of the cardiovascular system, and based on the concepts of active deformation and embedded muscle fibres. Specifically, here we deal with the modeling of the gross mechanics of the Left Ventricle (LV) which is strictly related to its pump function. As is well known, the effectiveness ...
G.T. Martin, and L. Angelone
Hologic, Inc., Bedford, Massachusetts, USA
Massachusetts General Hospital, Harvard Medical School, Marlborough, Massachusetts, USA
The NovaSure Endometrial Ablation System® is designed to remove the endometrial lining in the uterine cavity of women who suffer from menorrhagia. The NovaSure disposable device consists of a 2-pole, 4 electrode array that is inserted into the uterine cavity and deployed. We have developed a COMSOL Multiphysics model of the NovaSure ablation process. The model utilized COMSOL Multiphysics ...
Palo Alto Research Center
In this presentation we present our analysis of the PARC Nanocalorimeter. Calorimetry is basically the measuring of heat of chemical reactions or physical changes. Nanocalorimetry is Calorimetry at the Nanometer scale. The PARC Nanocalorimeter is a special type of Calorimeter, it consists of arrays of Nanocalorimeters. The PARC Nanocalorimeter is intended to be used for screening biochemical ...
N. El Khatib1, S. Genieys1, M. Zine2, and V. Volpert1
1Institut Camille Jordan, Université Claude Bernard, Lyon, France
2Département Maths & Informatique, Ecole Centrale de Lyon, Lyon, France
The development of atherosclerosis leads to the formation of an atheroma plaque which takes place in the artery. This plaque is composed of two parts: a lipid deposit and a fibrous cap. The fibrous cap covers the lipid deposit and isolates it from the blood flow. The blood flow that circulates in the artery modifies the geometry of the atheroma plaque and can cause dangerous effects, such as a ...
B. Boulbène, J. Morchain, and P. Schmitz
Université de Toulouse, NSA, UPS, INP, LISBP, Toulouse, France
We present numerical results involving microorganisms adhering to a plane surface submitted to a shear flow. The purpose is to have a better understanding of the removal mechanisms occurring during the cleaning in place of food processing equipments. The biological cell, i.e. the microorganism, is modelled as a rigid obstacle embedded in the bottom wall of the fluid domain. Shear induced ...